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Protein Coding Gene : Gadd45b growth arrest and DNA-damage-inducible 45 beta
Primary Identifier  MGI:107776 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17873
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within negative regulation of protein kinase activity; positive regulation of MAPK cascade; and regulation of cell cycle. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; future brain; hindlimb long bone; and sensory organ. Orthologous to human GADD45B (growth arrest and DNA damage inducible beta).
PHENOTYPE: Homozygous inactivation of this locus affects immune response. [provided by MGI curators]
  • synonyms:
  • myeloid differentiation primary response gene 118,
  • MGI:2143576,
  • expressed sequence AI323528,
  • MGD-MRK-36353,
  • Gadd45b,
  • myeloid differentiation primary response gene,
  • AI323528,
  • growth arrest and DNA-damage-inducible 45 beta,
  • Myd118
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