Primary Identifier | MGI:2147269 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 106947 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables zinc ion transmembrane transporter activity. Involved in zinc ion transmembrane transport. Acts upstream of or within several processes, including T cell homeostasis; chordate embryonic development; and zinc ion transport. Located in apical plasma membrane and hippocampal mossy fiber to CA3 synapse. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and yolk sac. Orthologous to human SLC39A3 (solute carrier family 39 member 3). PHENOTYPE: Homozygous null mice stressed with a zinc-deficient diet during pregnancy or at weaning exhibit a subtle increase in the sensitivity to abnormal morphogenesis of the embryo and to depletion of thymic pre-T cells, respectively. [provided by MGI curators] |