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Protein Coding Gene : Sgta small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha

Primary Identifier  MGI:1098703 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  52551
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable BAT3 complex binding activity; molecular adaptor activity; and protein dimerization activity. Predicted to be involved in several processes, including establishment of protein localization to membrane; protein complex oligomerization; and regulation of proteolysis involved in protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of TRC complex. Predicted to be active in membrane and presynapse. Predicted to be extrinsic component of synaptic vesicle membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and skin. Orthologous to human SGTA (small glutamine rich tetratricopeptide repeat co-chaperone alpha).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased neonatal death, subfertility, decreased body size, increased brain, intestine and heart weight, decreased serum insulin-like growth factor I level, large penis, and increased testis descent. [provided by MGI curators]
  • synonyms:
  • MGI:1915341,
  • expressed sequence AI194281,
  • DNA segment, Chr 10, ERATO Doi 190, expressed,
  • AI194281,
  • MGI:2143532,
  • MGC:6336,
  • D10Ertd190e,
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha,
  • Sgt,
  • 5330427H01Rik,
  • RIKEN cDNA 5330427H01 gene,
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing,
  • Sgta

Features --> Cross References

Genome

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0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For