Primary Identifier | MGI:1098703 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 52551 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable BAT3 complex binding activity; molecular adaptor activity; and protein dimerization activity. Predicted to be involved in several processes, including establishment of protein localization to membrane; protein complex oligomerization; and regulation of proteolysis involved in protein catabolic process. Predicted to be located in cytosol and nucleus. Predicted to be part of TRC complex. Predicted to be active in membrane and presynapse. Predicted to be extrinsic component of synaptic vesicle membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and skin. Orthologous to human SGTA (small glutamine rich tetratricopeptide repeat co-chaperone alpha). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased neonatal death, subfertility, decreased body size, increased brain, intestine and heart weight, decreased serum insulin-like growth factor I level, large penis, and increased testis descent. [provided by MGI curators] |