| Primary Identifier | MGI:1354165 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 50492 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables metalloendopeptidase activity. Acts upstream of or within intracellular signal transduction and peptide metabolic process. Predicted to be located in cytoplasm. Predicted to be active in mitochondrial intermembrane space. Is expressed in head mesenchyme and vertebral axis musculature. Orthologous to human THOP1 (thimet oligopeptidase 1). PHENOTYPE: Mice homozygous for a null allele display thrombocytopenia and other hematopoietic cells anomalies, decreased susceptibility to sepsis, increased susceptibility to EAE, behavioral abnormalities, and altered neurotransmitter turnover. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
