| Primary Identifier | MGI:1335091 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 16969 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and histone acetyltransferase binding activity. Involved in several processes, including double-strand break repair via classical nonhomologous end joining; hemopoiesis; and regulation of DNA-templated transcription. Part of DNA-dependent protein kinase complex. Colocalizes with site of double-strand break. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and limb bud. Orthologous to human ZBTB7A (zinc finger and BTB domain containing 7A). PHENOTYPE: Mice homozygous for a knock-out allele die around E16.5 due to anemia and exhibit a cell autonomous defect in early B cell development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
