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Protein Coding Gene : Dapk3 death-associated protein kinase 3
Primary Identifier  MGI:1203520 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  13144
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including cellular response to type II interferon; protein phosphorylation; and regulation of myosin II filament organization. Acts upstream of or within apoptotic signaling pathway. Located in PML body. Is expressed in heart; mammary gland epithelium; and notochord. Orthologous to human DAPK3 (death associated protein kinase 3).
PHENOTYPE: Mice homozygous for a gene-trapped allele exhibit embryonic lethality after blastocyst implantation. [provided by MGI curators]
  • synonyms:
  • Dapk3,
  • ZIP kinase,
  • death-associated protein kinase 3
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