| Primary Identifier | MGI:99259 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 17179 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in cytoplasm and membrane. Predicted to be active in plasma membrane. Is expressed in brain; gonad; hemolymphoid system gland; and intestine. Orthologous to human MATK (megakaryocyte-associated tyrosine kinase). PHENOTYPE: Homozygous mice are viable and fertile and appear normal. Unchallenged mutant mice exhibit no hematopoietic defects. SPKLS cell numbers are elevated. IL-7 induced BM cell proliferation and pre-B cell colony formation are enhanced. Antigen induced IFN-gamma secretion is reduced. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
