| Primary Identifier | MGI:104635 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 21886 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of canonical Wnt signaling pathway. Predicted to be located in focal adhesion and nuclear body. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; integumental system; limb; and sensory organ. Orthologous to human TLE2 (TLE family member 2, transcriptional corepressor). PHENOTYPE: Mice homozygous for a knock-out allele are viable and live into adulthood with no apparent pancreatic islet phenotypes. [provided by MGI curators] |