Primary Identifier | MGI:1927166 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 58250 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity. Acts upstream of or within several processes, including chondroitin sulfate biosynthetic process; post-anal tail morphogenesis; and skeletal system development. Predicted to be located in Golgi membrane. Is expressed in several structures, including alimentary system; central nervous system; ear; heart; and skeletal system. Orthologous to human CHST11 (carbohydrate sulfotransferase 11). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality associated with respiratory distress, dwarfism, and abnormal skeletal structures. [provided by MGI curators] |