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Protein Coding Gene : Rtcb RNA 2',3'-cyclic phosphate and 5'-OH ligase
Primary Identifier  MGI:106379 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  28088
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA ligase (ATP) activity; RNA ligase (GTP) activity; and vinculin binding activity. Acts upstream of or within in utero embryonic development and placenta development. Located in endoplasmic reticulum membrane and nuclear envelope. Is expressed in several structures, including early conceptus; gonad; heart; liver; and placenta. Orthologous to human RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase).
PHENOTYPE: Mice lacking expression in B cells show impaired immunoglobin secretion. [provided by MGI curators]
  • synonyms:
  • AI463255,
  • MGD-MRK-34072,
  • expressed sequence AI463255,
  • DNA segment, Chr 10, Wayne State University 52, expressed,
  • MGI:2143544,
  • RNA 2',3'-cyclic phosphate and 5'-OH ligase,
  • MGI:2143620,
  • D10Wsu52e,
  • AI255213,
  • Rtcb,
  • expressed sequence AI255213,
  • HSPC117
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