| Primary Identifier | MGI:1289172 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 213326 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable signaling receptor binding activity. Involved in pyramidal neuron development. Predicted to be located in Golgi apparatus; clathrin-coated vesicle; and endosome membrane. Human ortholog(s) of this gene implicated in arthrogryposis multiplex congenita-4. Orthologous to human SCYL2 (SCY1 like pseudokinase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality, absent gastric milk in neonates, postnatal growth retardation, sensory-motor deficits and limb grapsing. Mice homozygous for a conditional allele exhibit similar phenotypes with near complete loss of CA3 neurons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
