| Primary Identifier | MGI:101762 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 13713 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity and DNA-binding transcription factor activity. Acts upstream of or within angiogenesis; regulation of DNA-templated transcription; and wound healing. Located in nucleus. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and heart. Used to study congenital chylothorax. Orthologous to human ELK3 (ETS transcription factor ELK3). PHENOTYPE: Homozygotes for a null allele develop a vascular defect associated with lymphangiectasis and die prematurely due to respiratory failure resulting from chylothorax. Homozygotes for a different null allele show a transient delay in retinal primary plexus vascularization and tortuous retinal arteries. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
