Primary Identifier | MGI:96836 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 16993 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ether hydrolase activity; metalloaminopeptidase activity; and zinc ion binding activity. Predicted to be involved in leukotriene biosynthetic process and peptide catabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human LTA4H (leukotriene A4 hydrolase). PHENOTYPE: Mice homozygous for disruptions in this gene have grossly normal phenotypes. Inflammatory reactions are reduced as are some other immunological responses. [provided by MGI curators] |