| Primary Identifier | MGI:1929701 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 56307 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in N-terminal protein amino acid modification; peptidyl-methionine modification; and protein processing. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Is expressed in brain; cerebral cortex ventricular layer; cortical plate; and telencephalon. Orthologous to human METAP2 (methionyl aminopeptidase 2). PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality around E8.5, smaller size, failure to gastrulate, reduced cell proliferation and absence of a distinct mesoderm. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
