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Protein Coding Gene : Btg1 BTG anti-proliferation factor 1

Primary Identifier  MGI:88215 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  12226
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable enzyme binding activity. Acts upstream of or within negative regulation of cell population proliferation and protein methylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; central nervous system; limb; non-neural ectoderm; and sensory organ. Orthologous to human BTG1 (BTG anti-proliferation factor 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal neurogenesis in the dentate gyrus, decreased proliferation and increased apoptosis in the dentate gyrus and subventricular zone, impaired spatial learning and abnormal contextual conditioning behavior. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-1682,
  • AW546738,
  • BTG anti-proliferation factor 1,
  • Btg1,
  • expressed sequence AW546738,
  • MGI:2143593,
  • expressed sequence AI426953,
  • MGI:2143857,
  • AI426953

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For