Primary Identifier | MGI:1328351 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 67405 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable neuropeptide receptor binding activity and receptor ligand activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; neuropeptide signaling pathway; and visual learning. Predicted to be located in intracellular membrane-bounded organelle and neuronal cell body. Predicted to be active in axon terminus. Is expressed in several structures, including central nervous system; genitourinary system; heart ventricle; jaw; and retina. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human NTS (neurotensin). PHENOTYPE: Mice homozygous for a targeted null mutation are viable, fertile, and grossly normal, but display altered responses to antipsychotic drugs. [provided by MGI curators] |