|  Help  |  About  |  Contact Us

Protein Coding Gene : Ppp1r12a protein phosphatase 1, regulatory subunit 12A
Primary Identifier  MGI:1309528 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  17931
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including 14-3-3 protein binding activity; myosin phosphatase regulator activity; and protein kinase binding activity. Acts upstream of or within cellular response to xenobiotic stimulus; protein dephosphorylation; and regulation of nucleocytoplasmic transport. Located in A band and Z disc. Is expressed in several structures, including genital tubercle epithelium; sciatic nerve; telencephalon; urethra epithelium; and urothelium. Orthologous to human PPP1R12A (protein phosphatase 1 regulatory subunit 12A).
PHENOTYPE: Homozygous null mice die before E7.5. Mice homozygous for a smooth muscle specific conditional knockout exhibit altered intestinal smooth muscle contractility. [provided by MGI curators]
  • synonyms:
  • Ppp1r12a,
  • MGI:2143782,
  • Mypt1,
  • AV099298,
  • DNA segment, Chr 10, ERATO Doi 625, expressed,
  • MGI:2143509,
  • D10Ertd625e,
  • myosin phosphatase, target subunit 1,
  • expressed sequence AV099298,
  • RIKEN cDNA 1200015F06 gene,
  • MGI:1918986,
  • AA792106,
  • protein phosphatase 1, regulatory subunit 12A,
  • expressed sequence AA792106,
  • 1200015F06Rik,
  • MGI:1289205,
  • RIKEN cDNA 5730577I22 gene,
  • 5730577I22Rik,
  • MGI:1917922
Paste the following link
Lists
This ProteinCodingGene isn't in any lists. Upload a list.

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For





MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom