Primary Identifier | MGI:1289147 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 52679 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hepatocyte differentiation; regulation of cell cycle process; and trophoblast giant cell differentiation. Acts upstream of or within negative regulation of cell population proliferation and regulation of DNA-templated transcription. Located in nucleus. Is expressed in brain; embryo mesenchyme; and genitourinary system. Orthologous to human E2F7 (E2F transcription factor 7). PHENOTYPE: Mice homozygous for a knock-out allele develop normally through puberty and survive to old age. [provided by MGI curators] |