Primary Identifier | MGI:1202907 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 13008 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actinin binding activity. Predicted to be a structural constituent of muscle. Predicted to be involved in muscle tissue development and sarcomere organization. Predicted to be active in Z disc and nucleus. Is expressed in several structures, including cardiovascular system; central nervous system; cranium; genitourinary system; and gut. Orthologous to human CSRP2 (cysteine and glycine rich protein 2). PHENOTYPE: Mice homozygous for one null allele display increased neointima formation following arterial injury and increased migration of vascular smooth muscle cells in response to PDGF-BB. [provided by MGI curators] |