Primary Identifier | MGI:1855693 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 53605 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including chromatin binding activity; histone binding activity; and histone chaperone activity. Involved in positive regulation of neural precursor cell proliferation and positive regulation of neurogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including blood; forebrain; genitourinary system; liver; and nucleus pulposus. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human NAP1L1 (nucleosome assembly protein 1 like 1). PHENOTYPE: Mice homozygous for a homozygous mutation exhibit prenatal lethality and impaired neural progenitor cell proliferation and differentiation. [provided by MGI curators] |