| Primary Identifier | MGI:1330301 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 69181 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity; metal ion binding activity; and protein kinase activity. Predicted to be involved in several processes, including intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of calcineurin-NFAT signaling cascade; and positive regulation of glycogen biosynthetic process. Predicted to act upstream of or within peptidyl-tyrosine phosphorylation. Part of ribonucleoprotein complex. Is expressed in several structures, including brain; eye; genitourinary system; gut gland; and hemolymphoid system gland. Orthologous to human DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2). PHENOTYPE: Homozygous knockout affects ciliogenesis, which affects bone development and leads to perinatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
