| Primary Identifier | MGI:1859216 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 54140 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable V1A vasopressin receptor binding activity; peptide hormone binding activity; and vasopressin receptor activity. Involved in regulation of blood pressure. Acts upstream of or within regulation of systemic arterial blood pressure by vasopressin. Predicted to be located in endocytic vesicle and endosome. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human AVPR1A (arginine vasopressin receptor 1A). PHENOTYPE: Mice homozygous for disruptions in this gene display a stimulus processing deficit similar to that seen in schizophrenia. Anxiety-like behaviors are reduced in males but not females. B cell development is also affected. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
