| Primary Identifier | MGI:101857 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 14479 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine-type deubiquitinase activity. Involved in protein deubiquitination. Acts upstream of or within regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator. Predicted to be located in cytosol and nuclear body. Predicted to be active in nucleus. Is expressed in incisor; nasal cavity epithelium; nervous system; submandibular gland primordium; and thymus primordium. Orthologous to human USP15 (ubiquitin specific peptidase 15). PHENOTYPE: Mice homozygous for a knock-out allele or ENU induced allele exhibit resistance to pathological neuroinflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
