Primary Identifier | MGI:3619045 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 723962 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to mechanical stimulus; long-term synaptic potentiation; and negative regulation of macromolecule metabolic process. Located in extracellular exosome. Part of RISC complex. Is expressed in several structures, including brain and lung. Orthologous to human MIR26A2 (microRNA 26a-2). PHENOTYPE: Mice double homozygous for Mir26a-1 and Mir26a-2 fed a high-fat diet exhibit beta cell hyperproliferation and hyperplasia with increased obesity, and insulin resistance. [provided by MGI curators] |