| Primary Identifier | MGI:109247 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 13198 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including DNA-binding transcription factor binding activity; protein heterodimerization activity; and transcription regulator activator activity. Involved in several processes, including blood vessel development; intracellular signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within ER overload response; negative regulation of fat cell differentiation; and sensory perception of sound. Located in late endosome and nucleus. Part of CHOP-C/EBP complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in myxoid liposarcoma. Orthologous to human DDIT3 (DNA damage inducible transcript 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased apoptosis in different cell types. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
