Primary Identifier | MGI:1195275 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 107605 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables all-trans-retinol dehydrogenase (NAD+) activity and steroid dehydrogenase activity. Acts upstream of or within retinoid metabolic process and steroid metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including Rathke's pouch; central nervous system; genitourinary system; liver; and lung. Orthologous to human RDH16 (retinol dehydrogenase 16). PHENOTYPE: Mice homozygous for a null allele exhibit increased body weight, adipose tissue, and retinol levels. [provided by MGI curators] |