| Primary Identifier | MGI:1929282 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 56351 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables DNA polymerase binding activity and prostaglandin-E synthase activity. Involved in cyclooxygenase pathway and telomerase holoenzyme complex assembly. Acts upstream of with a positive effect on telomere maintenance via telomerase. Acts upstream of or within several processes, including glycogen biosynthetic process; nuclear receptor-mediated glucocorticoid signaling pathway; and prostaglandin biosynthetic process. Is active in cytosol. Is expressed in liver and skin. Orthologous to human PTGES3 (prostaglandin E synthase 3). PHENOTYPE: Disruption of gene function results in neonatal lethality, respiratory system abnormalities, as well as skin morphological and physiological defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
