| Primary Identifier | MGI:1929282 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 56351 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA polymerase binding activity. Involved in telomerase holoenzyme complex assembly. Acts upstream of with a positive effect on telomere maintenance via telomerase. Acts upstream of or within several processes, including glycogen biosynthetic process; nuclear receptor-mediated glucocorticoid signaling pathway; and prostaglandin biosynthetic process. Predicted to be located in actin filament; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of protein folding chaperone complex and telomerase holoenzyme complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including liver and skin. Orthologous to human PTGES3 (prostaglandin E synthase 3). PHENOTYPE: Disruption of gene function results in neonatal lethality, respiratory system abnormalities, as well as skin morphological and physiological defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
