| Primary Identifier | MGI:1919336 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 72002 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables zinc ion transmembrane transporter activity. Involved in zinc ion transmembrane transport. Acts upstream of or within cellular response to zinc ion starvation and positive regulation of mRNA splicing, via spliceosome. Located in basolateral plasma membrane. Is expressed in several structures, including branchial arch; genitourinary system; gut; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in myopia. Orthologous to human SLC39A5 (solute carrier family 39 member 5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered zinc homeostasis and increased susceptibility to zinc-induced pancretitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
