Primary Identifier | MGI:1351628 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 27370 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of ribosome. Predicted to be involved in cytoplasmic translation and negative regulation of RNA splicing. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in palatal shelf and secondary palate. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 10. Orthologous to human RPS26 (ribosomal protein S26). PHENOTYPE: Knockout in mouse oocytes results in arrested follicle development from pre-antral follicles to antral follicles and all oocytes die by P84 resulting in premature ovarian failure. [provided by MGI curators] |