| Primary Identifier | MGI:102700 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 16404 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Contributes to laminin binding activity. Acts upstream of or within blood vessel morphogenesis; cell adhesion; and cell migration. Located in several cellular components, including muscle tendon junction; neuromuscular junction; and sarcolemma. Part of integrin alpha7-beta1 complex. Is expressed in several structures, including alimentary system; heart; metanephros; musculature; and nervous system. Used to study congenital muscular dystrophy due to integrin alpha-7 deficiency. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (integrin subunit alpha 7). PHENOTYPE: Mice homozygous for disruptions of this gene display characteristics of muscular dystrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
