| Primary Identifier | MGI:108055 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 11923 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in amacrine cell differentiation and positive regulation of cell differentiation. Acts upstream of or within several processes, including Notch signaling pathway; camera-type eye development; and neurogenesis. Predicted to be active in nucleus. Is expressed in several structures, including future brain; male reproductive system; nervous system; retina; and urinary system. Orthologous to human NEUROD4 (neuronal differentiation 4). PHENOTYPE: Homozygotes for a targeted null mutation exhibit reduced growth, ataxia, and high postnatal mortality. Mutants show impaired postnatal cerebellar development, with thinner inner granular cell and molecular layers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
