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Protein Coding Gene : Tespa1 thymocyte expressed, positive selection associated 1

Primary Identifier  MGI:1914846 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  67596
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables phospholipase binding activity. Involved in several processes, including COP9 signalosome assembly; positive regulation of T cell differentiation in thymus; and positive regulation of T cell receptor signaling pathway. Acts upstream of or within TCR signalosome assembly. Located in cytoplasm. Part of TCR signalosome. Is expressed in ductus deferens; testis; thymus; and thymus primordium. Orthologous to human TESPA1 (thymocyte expressed, positive selection associated 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired late thymocyte development. [provided by MGI curators]
  • synonyms:
  • Tespa1,
  • thymocyte expressed, positive selection associated 1,
  • 5830405N20Rik,
  • RIKEN cDNA A430001F24 gene,
  • MGI:2444602,
  • RIKEN cDNA 5830405N20 gene,
  • Itprid3,
  • A430001F24Rik,
  • expressed sequence AI450549,
  • AI450549,
  • MGI:2143610

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Canonical gene --> Transcripts in specific strains.

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