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Protein Coding Gene : Tbc1d10a TBC1 domain family, member 10a
Primary Identifier  MGI:2144164 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  103724
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTPase activator activity and PDZ domain binding activity. Predicted to be involved in activation of cysteine-type endopeptidase activity and retrograde transport, endosome to Golgi. Predicted to be located in plasma membrane. Is expressed in renal calyx and vibrissa. Orthologous to human TBC1D10A (TBC1 domain family member 10A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased circulating LDL cholesterol levels, decreased circulating alanine transaminase and alkaline phosphatase levels, abnormal liver physiology, and increased chromosomal stability. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI447804,
  • TBC1 domain family, member 10a,
  • Tbc1d10a,
  • EPI64,
  • AI447804,
  • Tbc1d10,
  • TBC1 domain family, member 10
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