Primary Identifier | MGI:104749 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 18413 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity. Acts upstream of or within several processes, including negative regulation of meiotic nuclear division; positive regulation of peptidyl-tyrosine phosphorylation; and tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Is expressed in several structures, including aorta-gonad-mesonephros; future spinal cord; genitourinary system; submandibular gland; and trophectoderm. Orthologous to human OSM (oncostatin M). PHENOTYPE: Homozygous mutant mice display decreased noxious responses in models of acute thermal, mechanical, chemical, and visceral pain. [provided by MGI curators] |