Primary Identifier | MGI:1921552 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 74302 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatase activity and protein phosphatase binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; phosphatidylinositol metabolic process; and regulation of phosphatidylinositol dephosphorylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm and membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human MTMR3 (myotubularin related protein 3). PHENOTYPE: Homozygous mutation of this gene results in increased serum alkaline phosphatase level and, in males, impaired glucose tolerance. [provided by MGI curators] |