Primary Identifier | MGI:1913402 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 66152 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. Part of respiratory chain complex III. Is active in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X). PHENOTYPE: Mice homozygous for a knock-out allele show embryonic growth retardation, small egg cylinders, disorganized extraembryonic tissue, failure of primitive streak formation and gastrulation, and complete embryonic lethality by E9.5. [provided by MGI curators] |