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Protein Coding Gene : Polm polymerase (DNA directed), mu
Primary Identifier  MGI:1860191 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  54125
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable DNA-directed DNA polymerase activity. Acts upstream of or within B cell differentiation and somatic hypermutation of immunoglobulin genes. Predicted to be active in nucleus. Is expressed in muscle tissue and retina. Orthologous to human POLM (DNA polymerase mu).
PHENOTYPE: Mice homozygous for disruptions in this gene display an apparently normal phenotype. However, B cell maturation and proliferation is abnormal. [provided by MGI curators]
  • synonyms:
  • polymerase (DNA directed), mu,
  • MGI:2144181,
  • RIKEN cDNA B230309I03 gene,
  • MGI:2443119,
  • expressed sequence AI462166,
  • Tdt-N,
  • AI462166,
  • B230309I03Rik,
  • Polm
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