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Protein Coding Gene : Purb purine rich element binding protein B
Primary Identifier  MGI:1338779 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  19291
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; SMAD binding activity; and nucleic acid binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Acts upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. Is expressed in heart and hindlimb muscle. Orthologous to human PURB (purine rich element binding protein B).
  • synonyms:
  • MGD-MRK-34063,
  • Purb,
  • MGI:1923687,
  • AA114818,
  • DNA segment, Chr 11, Brigham & Women's Genetics 0414 expressed,
  • Cager-2,
  • D11Bwg0414e,
  • 2310015K15Rik,
  • RIKEN cDNA 2310015K15 gene,
  • expressed sequence AA114818,
  • purine rich element binding protein B,
  • MGI:3034759,
  • MGI:106370
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