| Primary Identifier | MGI:1890648 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 60530 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; magnesium ion binding activity; and microtubule severing ATPase activity. Involved in several processes, including male meiotic nuclear division; osteoblast differentiation; and osteoblast proliferation. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway. Located in nucleus and perinuclear region of cytoplasm. Is expressed in brain ventricular layer and inferior colliculus. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human FIGNL1 (fidgetin like 1). PHENOTYPE: Mice homozygous for a knock-out allele are embryonic lethal before E7.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
