| Primary Identifier | MGI:105056 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12808 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin monomer binding activity. Involved in several processes, including actin filament organization; embryonic pattern specification; and positive regulation of cell projection organization. Acts upstream of or within actin cytoskeleton organization and neural tube closure. Located in several cellular components, including growth cone; ruffle; and terminal web. Colocalizes with actin filament. Is expressed in several structures, including central nervous system; chordamesoderm; embryo mesenchyme; gut; and nose. Orthologous to human COBL (cordon-bleu WH2 repeat protein). PHENOTYPE: Animals homozygous for this mutation do not display a phenotype. However, the allele exacerbates the neural tube defects seen in the loop tail mouse. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
