Primary Identifier | MGI:1931026 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 58172 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription coactivator activity. Acts upstream of or within positive regulation of DNA-templated transcription. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including 1st branchial arch; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human SERTAD2 (SERTA domain containing 2). PHENOTYPE: Mice homozygous for a gene trap allele exhibit enhanced lipolysis, thermogenesis, and oxidative metabolism with resistance to diet induced obesity and steatosis and improved when fed a high fat diet. [provided by MGI curators] |