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Protein Coding Gene : Usp34 ubiquitin specific peptidase 34
Primary Identifier  MGI:109473 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  17847
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Predicted to be involved in positive regulation of canonical Wnt signaling pathway; protein K48-linked deubiquitination; and regulation of protein stability. Predicted to be active in cytosol and nucleus. Orthologous to human USP34 (ubiquitin specific peptidase 34).
PHENOTYPE: Mice homozygous for a conditional allele activated in early limb bud exhibit reduced osteogenic differentiation and bone formation. [provided by MGI curators]
  • synonyms:
  • U2af1-rs1 region 2,
  • A530081C03Rik,
  • ubiquitin specific peptidase 34,
  • MGD-MRK-38518,
  • RIKEN cDNA A530081C03 gene,
  • Murr2,
  • MGI:2441806,
  • Usp34
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1 Involved In Mutations

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0 UTRs

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Features --> Overlapping features

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7 Pathways

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Disease

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