Primary Identifier | MGI:2676893 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 387213 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in gene expression and mesonephric duct formation. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; cellular response to lipopolysaccharide; and negative regulation of osteoblast differentiation. Is expressed in embryo. Orthologous to human MIR217 (microRNA 217). PHENOTYPE: Mice homozygous for a null allele exhibit pancreatic acinar-to-ductal metaplasia in vitro and increased susceptibility to induced pancreatitis. [provided by MGI curators] |