Primary Identifier | MGI:104667 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 15366 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cargo receptor activity. Involved in hyaluronan catabolic process and receptor-mediated endocytosis. Predicted to be located in centrosome; cytosol; and spindle. Is expressed in bulbar cushion; ovary; and testis. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human HMMR (hyaluronan mediated motility receptor). PHENOTYPE: Mice homozygous for mutations of this gene exhibit impaired fertility and are less susceptible to the formation of aggressive fibromatosis. [provided by MGI curators] |