Primary Identifier | MGI:1916433 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 69183 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity and signaling receptor binding activity. Involved in regulation of lipid metabolic process. Acts upstream of or within positive regulation of D-glucose import; positive regulation of MAPK cascade; and positive regulation of small molecule metabolic process. Located in extracellular space. Part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and skeleton. Orthologous to human C1QTNF2 (C1q and TNF related 2). PHENOTYPE: Mice homozygous for a knock-out allele show decreased body weight, reduced adiposity, increased metabolic rate and energy expenditure, enhanced adipose tissue lipolysis, and altered hepatic and plasma lipid profiles. [provided by MGI curators] |