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Protein Coding Gene : Garin3 golgi associated RAB2 interactor 3
Primary Identifier  MGI:3650836 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  432552
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Acts upstream of or within several processes, including acrosome assembly; single fertilization; and vacuole organization. Located in Golgi apparatus. Is active in sperm head. Orthologous to human GARIN3 (golgi associated RAB2 interactor family member 3).
PHENOTYPE: Homozygous null males are infertile, with impaired sperm motility, abnormal sperm head and acrosome morphology, and impaired sperm binding to and penetration of the zona pellucida. [provided by MGI curators]
  • synonyms:
  • OTTMUSG00000005491,
  • Garin3,
  • golgi associated RAB2 interactor 3,
  • Fam71b,
  • family with sequence similarity 71, member B,
  • predicted gene, OTTMUSG00000005491,
  • MGI:6885577
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