Primary Identifier | MGI:1915317 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 68067 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; regulation of double-strand break repair; and response to ionizing radiation. Predicted to be located in nucleoplasm. Predicted to be part of Mre11 complex. Predicted to be active in nucleus. Orthologous to human MRNIP (MRN complex interacting protein). PHENOTYPE: Mice homozygous for a null allele exhibit reduced male fertility, small testes, oligozoospermia, asthenozoospermia, and abnormal male meiosis. [provided by MGI curators] |