Primary Identifier | MGI:107498 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 17001 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables leukotriene-C4 synthase activity and lipid binding activity. Acts upstream of or within leukotriene metabolic process. Predicted to be located in endoplasmic reticulum membrane and nuclear outer membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human LTC4S (leukotriene C4 synthase). PHENOTYPE: Mice homozygous for disruptions in this gene display abnormal inflammatory and hypersensitivity reactions but are otherwise normal. [provided by MGI curators] |