| Primary Identifier | MGI:1924621 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 77371 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable SNARE binding activity and zinc ion binding activity. Acts upstream of or within cholesterol homeostasis; positive regulation of protein secretion; and regulation of cholesterol transport. Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Is expressed in embryo. Orthologous to human SEC24A (SEC24 homolog A, COPII coat complex component). PHENOTYPE: Mice homozygous for a null allele exhibit decreased circulating cholesterol level, decreased circulating LDL cholesterol level, and abnormal liver physiology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
